Patients Characteristics and Preliminary Outcomes of Heart Failure Registry in A Middle-Income Country: Persian Registry of Cardiovascular Disease/Heart Failure (PROVE/HF)
AbstractBackground: The Persian Registry of Cardiovascular disease/Heart Failure (PROVE/HF) aimed to studied the demographic, clinical, and diagnostic characteristics and treatment of patients hospitalized for heart failure (HF) and to follow them for short- and long-term outcomes. Its pilot phase started in 2015 in Isfahan aiming to evaluate its feasibility to be scaled up at the national level in later stages. This article describes the method and preliminary results of the first year registry. Materials and Methods: Information of hospitalized patients with preserved and low ejection fraction, were gathered. Patients were followed for 1, 6, and 12 months. During follow-up, information of the patients’ current status, medications used during hospitalization, and in case of death, the cause and place were assessed. Result: PROVE/HF enrolled 787 patients in the first year. The mean age of patients was 70.74 ±12.01 years, and 60.7% of them were men. The most frequent risk factors for the development of HF in the recruited patients was ischemic heart disease (77.9%), and hypertension (63.7%), respectively. The re-admission rate for patients with HF was at least once in 16% and continued until the fifth to ninth re-admission over a one-year period. Among 787 registered patients, 30.9% died in the first year of follow-up, and the in-hospital mortality was 6.2%. The mean hospitalization period was 4.88 days, and 64.2% were hospitalized for >3 days. Conclusion: The annual rate of re-admission and mortality was high, and the use of medication was less than the recommended one inaccordance with the guidelines for the treatment of heart failure. [GMJ.2018;7:e1026]
Amiri Z, Farazmand A, Tolooei M. Causes of Hospitalization of elderly people in hospitals in Rasht in 1379, to study the issues of the elderly in Iran and the world. Tehran: Ashena Book Publishers.; 2002. p.103-99. [in Persian]
Akbari M. According ten years of the Islamic Republic of Iran on the international goals on Population and Development. First Edition. Tehran: Ministry of Health and Medical Education Department of Health.; 2004. p.14-21. [in Persian]
Mahan LK, Escott- Stump S. Krauses Food, Nutrition and Diet Theraoy. 5th edition. Philadelphia: W.B Saunders Company.; 2008.p:1021.
Sarrafzadegan N, Kelishadi R, Baghaei A, HusseinSadri G, Malekafzali H, Mohammadifard N, et al. Metabolic syndrome: an emerging public health problem in Iranian Women: Isfahan Healthy Heart Program. Int J Cardiol. 2008; 131:90–6. https://doi.org/10.1016/j.ijcard.2007.10.049 PMid:18190978
Talaei M, Sarrafzadegan N, Sadeghi M, Oveisgharan S, Marshall T, Thomas GN, et al. Incidence of Cardiovascular Diseases in an Iranian Population: The Isfahan Cohort Study, Incidence of cardiovascular diseases in an Iranian population: The Isfahan cohort study. Arch Iran Med. 2013; 16: 138–44. PMid:23432164
Riegel B, Carlson B. Facilitators and barriers to heart failure self-care. Patient EducCouns. 2002; 46(4): 287-95. https://doi.org/10.1016/S0738-3991(01)00165-3
2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task, Downloaded from http://circ.ahajournals.org/ by guest on August 13, 2013.
Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J. 2008; 29:2388–442. https://doi.org/10.1093/eurheartj/ehn309 PMid:18799522
Cheraghi M, Sadeghi M, Sarrafzadegan N, Pourmoghadas A, Ramezani MA. Prognostic factors for survival at 6-month follow-up of hospitalized patients with decompensated congestive heart failure. ARYA Atherosclerosis Journal. 2010; 6(3):112-8.
Ahmed A. DEFEAT - Heart Failure: a guide to management of geriatric heart failure by generalist physicians. Minerva Med. 2009; 100(1):39-50. PMid:19277003 PMCid:PMC2914573
Jessup M, Brozena S. Heart Failure. N Engl J Med. 2003; 348: 2007-18. https://doi.org/10.1056/NEJMra021498 PMid:12748317
Kato N, Kinugaw K, Ito N, Yao A, Watanab M, ImaiY, Takeda N, Hatano M, Kasoma K. Adherence to self-care behavior and factors related to this behavior among patients with heart failure in Japan. Heart Lung. 2009; 38:398-409. https://doi.org/10.1016/j.hrtlng.2008.11.002 PMid:19755190
Koelling TM, Chen RS, Lubwana RN, L'Italien GJ, Eagle KA. The expanding national burden of heart failure in the United States: the influence of heart failure in women. Am Heart J. 2004; 147:74-8. https://doi.org/10.1016/j.ahj.2003.07.021 PMid:14691422
Woodend AK, Sherrard H, Fraser M, Stuewe L, Cheung T, Struthers C. Telehome monitoring in patients with cardiac disease who are at high risk of readmission. Heart Lung. 2008;37(1):36-45. https://doi.org/10.1016/j.hrtlng.2007.04.004 PMid:18206525
Johansson P, Dahlström U, Broström A. Factors and interventions influencing health-related quality of life in patients with heart failure: a review of the literature. Eur J Cardiovasc Nurs. 2006; 5:5-15. https://doi.org/10.1016/j.ejcnurse.2005.04.011 PMid:15967727
Design & Implementing of health information system: ministry of health and medical education–deputy of research & technology, 2005.Available at: http://www.allhealth.org/publications/health_information_technology/health_information_technology_toolkit.asp.
Givi M, Sarrafzadegan N, Garakyaraghi M, et al. Persian registry of cardiovascular disease (PROVE): Design and methodology. ARYA Atheroscler 2017;13(5):236-44. PMid:29371870 PMCid:PMC5774796
Sato N, Kajimoto K, Asai K, Mizuno M, Minami Y, Nagashima M. Acute decompensated heart failure syndromes (ATTEND) registry. A prospective observational multicenter cohort study: rationale, design, and preliminary data. Am Heart J. 2010;159(6): 949-55. https://doi.org/10.1016/j.ahj.2010.03.019 PMid:20569705
Jonsson A, Edner M, Alehagen U, Dahlstro U. Heart failure registry: a valuable tool for improving the management of patients with heart failure. Eur J Heart Fail. 2010; 12: 25–31. https://doi.org/10.1093/eurjhf/hfp175 PMid:20023041
Laothavorn P, Hengrussamee K, Kanjanavanit K, Moleerergpoom W, Laorakpongse D, Pachirat O, et al. Thai Acute Decompensated Heart Failure Registry (Thai ADHERE).CVD Prev Control. 2010; 5:89–9. https://doi.org/10.1016/j.cvdpc.2010.06.001
Theoretical Principles of Testing and Standardization, 2015.Available at: http://ssu.ac.ir/cms/fileadmin/user_upload/Daneshkadaha/dbehdasht/tose_amuzesh/mataleb_amoozeshi/workshop/marahel_sakht_azmoon.docx[in (Persian])
Huffman DA. A method for the construction of minimum-Redundancy codes. Proceedings of the IRE. 1952; 40(9); 1098- 101. https://doi.org/10.1109/JRPROC.1952.273898
Golin MJ, Kenyon C, Young NE. Huffman coding with unequal letter costs. Montreal, Quebec, Canada: ACM.; 2002. p. 785-91. https://doi.org/10.1145/509907.510020
Hai JJ, Chan PH, Huang D, Ho MH, Ho CW, Cheung E, et al. Clinical characteristics, management, and outcomes of hospitalized heart failure in a Chinese population—The Hong Kong Heart Failure Registry. J Card Fail. 2016; 22:600–8. https://doi.org/10.1016/j.cardfail.2016.03.007 PMid:27002944
O'Connor CM, Stough WG, Gallup DS, Hasselblad V, Gheorghiade M. Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry. J Card Fail. 2005; 11:200-5. https://doi.org/10.1016/j.cardfail.2004.08.160 PMid:15812748
Maggioni AP, Dahlström U, Filippatos G, Chioncel O, Crespo Leiro M, Drozdz J, et al. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot). Eur J Heart Fail. 2013; 15: 808-17. https://doi.org/10.1093/eurjhf/hft050 PMid:23537547
Gheorghiade M, Abraham WT, Albert NM, Greenberg BH, O'Connor CM, She L, et al. Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure. JAMA. 2006;296:2217-26. https://doi.org/10.1001/jama.296.18.2217 PMid:17090768
Sulaiman K, Panduranga P, Al-Zakwani I, Alsheikh-Ali AA, Al Habib KF, Al-Suwaidi J, et al. Clinical characteristics, management, and outcomes of acute heart failure patients: observations from the Gulf acute heart failure registry (Gulf CARE). Eur J Heart Fail. 2015; 17(4):374-84. https://doi.org/10.1002/ejhf.245 PMid:25739882
Mebazaa A, Parissis J, Porcher R, Gayat E, Nikolaou M, Boas FV, et al. Short-term survival by treatment among patients hospitalized with acute heart failure:the global ALARM-HF registry using propensity scoring methods. Intensive Care Med. 2011; 37:290–301. https://doi.org/10.1007/s00134-010-2073-4 PMid:21086112
Oliva F, Mortara A, Cacciatore G, Chinaglia A, Di Lenarda A, Gorini M, et al. Acute heart failure patient profiles, management and in-hospital outcome: results of the Italian Registry on Heart Failure Outcome. Eur J Heart Fail. 2012; 14:1208–17. https://doi.org/10.1093/eurjhf/hfs117 PMid:22833614
James L, Januzzi Jr, Douglas LM.Chapter 23 of Braunwald's Heart Disease, A Textbook of Cardiovascular Medicine: Clinical Assessment of Heart Failure. 10th Edition. Philadelphia: Elsevier Science.; 2014
Drazner, MH,Hellkamp AS, Leier CV, Shah MR, Miller LW, Russell SD, et al. Value of clinician assessment of hemodynamics in advanced heart failure: The escape trial. Circ Heart Fail. 2008; 1: 170–7. https://doi.org/10.1161/CIRCHEARTFAILURE.108.769778 PMid:19675681 PMCid:PMC2724723
Heywood JT, Linda L. ADHERE®: Improving the Medical Management and Quality of Care of Heart Failure Patients, A Special Report from the ADHERE Investigator Meeting. New Orleans, Louisiana. 2004.
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016; 37:2129-200. https://doi.org/10.1093/eurheartj/ehw128 PMid:27206819
West R, Liang L, Fonarow GC, Kociol R, Mills RM, O'Connor CM, et al. haracterization of heart failure patients with preserved ejection fraction: A comparison between ADHERE-US registry and ADHERE-International registry. Eur J Heart Fail. 2011; 13: 945-52. https://doi.org/10.1093/eurjhf/hfr064 PMid:21712289 PMCid:PMC3157970
Fonarow GC, Heywood JT, Heidenreich PA, Lopatin M, Yancy CW; ADHERE Scientific Advisory Committee and Investigators. Temporal trends in clinical characteristics, treatments, and outcomes for heart failure hospitalizations, 2002 to 2004: findings from Acute Decompensated Heart Failure National Registry (ADHERE). Am Heart J. 2007; 153:1021-8. https://doi.org/10.1016/j.ahj.2007.03.012 PMid:17540205
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).