Incidental Abdominal Aortic Aneurysm in the Psoriasis Patient: A Case Report and Review of Literature
Abstract
Background: Psoriasis is defined as a chronic inflammatory disease involving keratinocytes hyperproliferation of the epidermis with the acceleration in the epidermal turnover time, which is affected by various factors including genetic, immunologic, and environmental factors. There is a high risk for the development of premature cardiovascular diseases among patients with psoriasis as well as one of the life-threatening events is an aortic aneurysm (AA). Case Report: We report a 60-year-old man with the diagnosed psoriatic disease that an enlargement of the abdominal AA was incidentally found by annual check-up. Conclusion: Further large-scale studies are needed to find the prevalence of abdominal AA in psoriasis and the appropriate screening time of that in this disease. [GMJ.2018;7:e1168]References
Ghasemi M, Ghafarpour G, Behrangi E, Ghaffarpour G, Azizian Z. Determining the Prevalence and Types of Nail Involvement in Patients with Severe Acne Vulgaris Who Referred to Clinic of Dermatology of Rasoul-e-akram Hospital During 2010-2011. Internal Medicine and Medical Investigation Journal. 2017 May 22;2(2):57-62.
https://doi.org/10.24200/imminv.v2i2.56
Sharma YK, Parakash N, Gupta A, Bansal P. Lingering immune dysregulation of inflammatory dermatoses, particularly psoriasis, probably derives metabolic syndrome culminating in cardiovascular damage and needs preventive public health guidelines as well as comprehensive management. Med J DY Patil Univ. 2016;9:168-76.
https://doi.org/10.4103/0975-2870.177653
Erneste FC, Sanchez-menendez M, Wilton KM, Crowson CS, Matteson EL, Maradit Kremers H. Cardiovascular risk profile at the onset of psoriatic arthritis: a population-based cohort study. Arthritis care res (Hoboken).2015 jul;67(7):1015-21.
https://doi.org/10.1002/acr.22536
PMid:25581120 PMCid:PMC4482766
Patel RV, Shelling ML, Prodanovich S, Federman DG, Kirsner RS. Psoriasis and vascular disease-risk factors and outcomes: a systemic review of the literature. J Gen Intern Med. 2011 Sep. 26(9):1036-49.
https://doi.org/10.1007/s11606-011-1698-5
PMid:21472501 PMCid:PMC3157521
Meffert J, James WD. Psoriasis: practice essentials, background, pathophysiology. Medscape.
Krueger JG, Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis. Ann Rheum Dis.2005 mar.64 Suppl 2:ii30-36.
https://doi.org/10.1136/ard.2004.031120
PMid:15708932 PMCid:PMC1766865
Rahimi SA, Rowe VL. Abdominal aortic aneurysm: practice essentials, background, anatomy. Medscape. 2018 Nov.
Teague H,Ng Q, Purmalek M, Natarajan B, Salahuddin T, Stansky E, Aridi T, Playford MP, Kaplan MJ, Mehta NN. Abstract, 11890:S100A8/A9 is increased in psoriasis serum, relates to vascular diseases and activates human endothelial cells. Circulation. 2015;132:A11890
Naik HB, Natarajan B, Stansky E, Ahlman MA, Teague H, Salahuddin T, et al. Severity of psoriasis associates with aortic vascular inflammation detected by FDG PET/CT and neutrophil activation in a prospective observational study. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2667-76
https://doi.org/10.1161/ATVBAHA.115.306460
PMid:26449753 PMCid:PMC4662627
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).