Comparison of Auditory Brain Stem Responses and Otoacoustic Emission of Autism with Healthy Children
AbstractBackground: Autism is a neurodevelopment disorder, including difficulty in establishing relationships and social interaction, difficulty in communication, performing restricted, and repetitive behaviors. The impaired reception and integration of sensory information especially auditory data are one of the main characteristics of children with autism. According to various studies, the brain stem plays a key role in the reception and integration of auditory and sensory data. Hence, this study aims to comparison auditory brain stem responses (ABR) and otoacoustic emission (OAE) of autism patients with healthy children. Materials and Methods: This case-control study was performed on 20 autism children (4-8 years old) as case group who referred to psychiatry clinics affiliated with Tabriz University of Medical Sciences and 20 healthy age-matched as the control group. The severity of autism was evaluated by the Gilliam Autism Rating Scale (GARS). Also, ABR and OAE were recorded, and all data compared with the healthy children. Results: The latencies between the waves III-V and I-V bilaterally, and wave V bilaterally and wave I in the left ear showed a significant increase in children with autism compared to the healthy group. Conclusion: This study shows that there was a reduced nerve conduction velocity in the auditory pathway of the brain stem in children with autism compared to healthy children. [GMJ.2020;9:e1937]
Trull TJ, Vergés A, Wood PK, Jahng S, Sher KJ. The structure of Diagnostic and Statistical Manual of Mental Disorders (text revision) personality disorder symptoms in a large national sample. Personality Disorders: Theory, Research, and Treatment. 2012;3(4):355.
Ricketts J. Research review: Reading comprehension in developmental disorders of language and communication. J Child Psychol Psychiatr. 2011;52(11):1111-23.
Åsberg J, Kopp S, Berg-Kelly K, Gillberg C. Reading comprehension, word decoding and spelling in girls with autism spectrum disorders (ASD) or attention-deficit/hyperactivity disorder (AD/HD): Performance and predictors. Int J Lang Commun Disord. 2010;45(1):61-71.
Calloway CJ. Understanding the Nature of Autism: A Practical Guide. Focus Autism Other Dev Disabl. 1998 1;13(3):18 .
Klin A. Autismo e síndrome de Asperger: uma visão geral Autism and Asperger syndrome: an overview. Rev Bras Psiquiatr. 2006;28(Supl I):S3-11.
Cohen DJ, Volkmar FR. Handbook of autism and pervasive developmental disorders: John Wiley & Sons Inc; 1997.
Adams L. Oral-Motor and motor-speech characteristics of children with autism. Focus Autism Other Dev Disabl. 1998;13(2):108-12.
Neisworth JT, Wolfe PS. The autism encyclopedia: Paul H Brookes Publishing; 2005.
Johnson N, Frenn M, Feetham S, Simpson P. Autism spectrum disorder: parenting stress, family functioning and health-related quality of life. Families, systems, & health. 2011;29(3):232.
Bolay H, Bayazit YA, Gündüz B, Ugur AK, Akçali D, Altunyay S, et al. Subclinical dysfunction of cochlea and cochlear efferents in migraine: An otoacoustic emission study. Cephalalgia. 2008;28(4):309-17.
Grewe TS, Danhauer JL, Danhauer KJ, Thornton A. Clinical use of otoacoustic emissions in children with autism. Int J Pediatr Otorhinolaryngol. 1994;30(2):123-32.
Tharpe AM, Bess FH, Sladen DP, Schissel H, Couch S, Schery T. Auditory characteristics of children with autism. Ear Hear . 2006;27(4):430-41.
Corbett E, Prelock PA, editors. Language play in children with autism spectrum disorders: implications for practice. Seminars in speech and language; 2006: Copyright© 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.
Gaffney GR, Kuperman S, Tsai LY, Minchin S. Morphological evidence for brainstem involvement in infantile autism. Biol Psychiatry. 1988;24(5):578-86.
Skoyles J. Is autism due to cerebral-cerebellum disconnection? Med Hypotheses. 2002;58(4):332-6.
Ingram JL, Stodgell CJ, Hyman SL, Figlewicz DA, Weitkamp LR, Rodier PM. Discovery of allelic variants of HOXA1 and HOXB1: genetic susceptibility to autism spectrum disorders. Teratology. 2000;62(6):393-405.
Launay J-M, Bursztejn C, Ferrari P, Dreux C, Braconnier A, Zarifian E, et al. Catecholamines metabolism in infantile autism: a controlled study of 22 autistic children. J Autism Dev Disord. 1987;17(3):333-47.
Wong V, Wong SN. Brainstem auditory evoked potential study in children with autistic disorder. J Autism Dev Disord. 1991;21(3):329-40.
Thivierge J, Bedard C, Cote R, Maziade M. Brainstem auditory evoked response and subcortical abnormalities in autism. Am J Psychiatry. 1990;147(12):1609.
Bomba MD, Pang EW. Cortical auditory evoked potentials in autism: A review. Int J Psychophysiol. 2004;53(3):161-9.
Flint P. Cummings otolaryngology head and neck surgery Vol 3. 2010.
Rosenhall U, Nordin V, Brantberg K, Gillberg C. Autism and auditory brain stem responses. Ear Hear . 2003;24(3):206-14.
Møller AR, Jannetta P. Neural generators of the auditory brainstem response. The auditory brainstem response. 1985:13-31.
Maziade M, Merette C, Cayer M, Roy MA, Szatmari P, Cote R, et al. Prolongation of brainstem auditory-evoked responses in autistic probands and their unaffected relatives. Arch Gen Psychiatry. 2000;57(11):1077-83.
Taylor M, Rosenblatt B, Linschoten L. Auditory brainstem response abnormalities in autistic children. Can J Neurol Sci. 1982;9(4):429-33.
Tas A, Yagiz R, Tas M, Esme M, Uzun C, Karasalihoglu AR. Evaluation of hearing in children with autism by using TEOAE and ABR. Autism. 2007;11(1):73-9.
Naderpour M, Mortazavi F, Jabbari Moghaddam Y. Auditory brain stem response and otoacoustic emission results in children with end -stage renal disease.IJPORL 2011;( 75 )704-707.7
Courchesne E, Courchesne RY, Hicks G, Lincoln AJ. Functioning of the brainstem auditory pathway in non-retarded autistic individuals. Electroencephalogr Clin Neurophysiol. 1985;61(6):491-501.829.
Rumsey JM, Grimes A, Pikus A, Duara R, Ismond D. Auditory brainstem responses in pervasive developmental disorders. Biol Psychiatry . 1984.930.
Khalfa S, Bruneau N, Roge B, Georgieff N, Veuillet E, Adrien JL, et al. Peripheral auditory asymmetry in infantile autism. Eur J Neurosci . 2001;13(3):628-32.031.
Lemaire MC, Beutter P. Brainstem auditory evoked responses in patients with tinnitus. Audiology. 1995;34(6):287-300.132.
Gilliam JE. GARS-2: Gilliam autism rating scale: Pro-ed; 2006.233.
Hamidi Nahrani M, Sedaie M, Fatahi J, Sarough Farahani S, Faghihzadeh D. Auditory brainstem responses in autistic children in comparison with normal children. Bimonthly Audiology-Tehran University of Medical Sciences. 2007;16(2):16-22.334..
Melda A et al.Development of neural responses to hearing their own name in infants at low and high risk for autism spectrum disorder. Dev Cogn Neurosci .2020 41.100739435.
Doaa. E, et al.. Binaural interaction component of the auditory brainstem response in children with autism spectrum disorder. Int J Pediatr Otorhinolaryngol . 2020.131.109850.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).