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Combined Factor V and Factor VIII Deficiency: A Case Report

Ehsan Shahverdi, Hassan Abolghasemi, Fardin Dolatimehr, Sara Beheshtian, Shima Melatshahi Chaeichi, Avishan Masoumi

Background: Combined factor V and factor VIII deficiency (F5F8D, OMIM 227300) is a rare autosomal recessive bleeding disorder. It seems more common among Jews and Iranians, particularly in regions with frequent consanguineous marriages. Case Report: We describe a 5-yearold  girl  born  out  of  consanguineous  marriage  with  a  complaint  of  prolonged  bleeding  after dental extraction. There were no history of spontaneous bleeding and other coagulation defect symptoms. Conclusion: In frequent consanguineous marriage regions, inherited deficiency of factor V and VIII should be considered in patients with coagulation defect symptoms.[GMJ. 2016;5(1):42-44]

Combination; Factor V; Factor VIII

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