Epidemiology of Stroke in Iran

  • Kavian Ghandehari FLSP RCPC, Stroke & Cerebrovascular Disease Subspecialist, Director of Stroke Program, Mashhad University of Medical Sciences
Keywords: Stroke, Epidemiology, Iran.


Numerous hospital-based stroke registries have been developed in Iran during last decade. Khorasan Stroke Registry, Khorasan Posterior Circulation Stroke Registry, Khorasan Pediatric Stroke Registry and Khorasan Stroke in Young Adults Registry are among these published registries. Meanwhile, There is only one epidemiologic deigned study of stroke in Iran and Middle East. Based on this standard epidemiologic study; The crude annual incidence rate of First Ever Stroke (FES) is 139 (95% CI, 128 to 149) per 100 000; for men, 144 (95% CI, 128 to 159), and for women, 133 (95% CI, 118 to 148). The incidence rates increases significantly with each decade of life and is similar in men and women. Subtypes of FES in 81.9%  of patients is ischemic stroke,12.7% is intracerebral hemorrhage, and 2.4% have subarachnoid hemorrhage. The crude annual incidence rate per 100 000 inhabitants is 113 (95% CI, 104 to 123) for ischemic stroke, 18 (95% CI, 14 to 21) for intracerebral hemorrhage and 3 (95% CI, 2 to 5) for subarachnoid hemorrhage. Ischemic strokes are occurring approximately 1 decade earlier in Iran than in other countries.


Ghandehari K, Etemadi MM. Risk factors and etiology of transient ischemic attacks in patients with brain infarction. ARYA Atheroscler. 2010 ;3(1).

Ghandehari K. Evaluation of hemorrhagic infarction in stroke patients. Yafte Journal of Lorestan University of Medical Sciences 2005; 24: 10-11.

Ghandehari K, Mood ZI. Cardioembolic strokes in Eastern Iran and the importance of rheumatic valvular disease. Turkish Journal of Medical Sciences. 2007 ;36(6):361-4.

Ghandehari K, Shuaib A. Risk factors for leukoaraiosis in North American and Iranian stroke patients. Iranian Journal of Medical Sciences. 2015 ;30(4):165-8.

Ghandehari K. Evaluation of early seizures in stroke patients. Journal of Babol University of Medical Sciences, 2005, 7 (4); 14-15.

Ghandehari K, Izadi Z. The Khorasan Stroke Registry: results of a five-year hospital-based study. Cerebrovascular Diseases. 2006 ;23(2-3):132-9.

FLSP KG, Izadi-Mood Z. Khorasan stroke registry: analysis of 1392 stroke patients. Archives of Iranian medicine. 2007;10(3):327-34.

Ghandehari K, Asian Synopsis of stroke, 1st edition, 2011, Mashad, Mashhad University Publications, 68-70

Ghandehari K. Comments on the Asian stroke criteria. Neural Regen Res. 2009 ;4(11):958-60.

Ghandehari K, Mouradian M, Izadimoud Z, Salam A. Reliability of the Practical Asian Criteria for classification of brain infarct. Arch Iranian Med, 2004;7 (4), 1-5.

Ghandehari K, Mouradian M. Rheumatic valvular disease and stroke in eastern Iran. PKJFM. 2004;8:2-5.

Ghandehari K, Ghandehari K. Interesting basis of vertebrobasilar arterial territory. Iranian journal of neurology. 2012;11(3):111.

Ghandehari K, Etemadi MM, Nikrad M, Shakeri MT, Mansoori M. Khorasan Posterior Circulation Stroke Regis-try: a Hospital-Based Study. Iranian Journal of Medical Sciences. 2015;33(2):67-73.

Ghandehari K, Izadi-Mood Z. Incidence and etiology of pediatric stroke in southern Khorasan. ARYA Atheroscler. 2010 ;3(1).

Ghandehari K, Moud ZI. Incidence and etiology of ischemic stroke in Persian young adults. Acta neurologica scandinavica. 2006 ;113(2):121-4.

FLSP KG, Izadi-Mood Z. Etiology of young adult onset brain infarction in Iran. Archives of Iranian Medicine. 2006 ;9(3):240-3.

Ghandehari K, Mouradian M. Rheumatic valvular disease and stroke in eastern Iran. PKJFM. 2004;8:2-5.

Ghandehari K, Shuaib A. Prevalence of patent foramen ovale detected by transcranial color coded duplex sonography in cryptogenic stroke patients.Iranian Journal of Radiology, 2004; 2: 104-107

Azarpazhooh MR, Etemadi MM, Donnan GA, Mokhber N, Majdi MR, Ghayour-Mobarhan M, et al. Excessive incidence of stroke in Iran evidence from the Mashhad stroke incidence study (MSIS), a population-based study of stroke in the Middle East. Stroke. 2010 ;41(1):e3-10.

Ghandehari K, Shuaib A. SILENT BRAIN INFARCTION IN STROKE PATIENTS: A PILOT DOUBLE-CENTER STUDY. Medical Journal of The Islamic Republic of Iran (MJIRI). 2005 ;18(4):341-3.

Ghandehari K, Riasi HR. Evaluation of topography, etiology of multi-infarct dementia in the stroke patients. Journal of Babol University of Medical Sciences 2007; 9: 29-37.

Ghandehari K, Shuaib A. Topography of Carotid sten in ischemic CVA Patients within two North American and Iranian Races. Journal of Ardabil University of Medical Sciences. 2007 ;7(2):160-4.

Ghandehari K, Shuaib A. Comparison of the topography of carotid territory stenosis in north American and Iranian stroke patients. Journal of Yazd University of Medical Sciences, 2006; 14: 20-23.

Hosseini AA, Sobhani-Rad D, Ghandehari K, Benamer HT. Frequency and clinical patterns of stroke in Iran-Systematic and critical review. BMC neurology. 2010 ;10(1):1.

Ghandehari K, Izadi Mood Z. Atherosclerosis risk factors and etiologic mechanisms of lacunar stroke. ARYA Atheroscler. 2010 ;2(2).

Ghandehari K, Shuaib A. Etiologic overlaps based on the brain infarct topography. Journal of Research in Medical Sciences. 2005 ;10(4):217-21.

Ghandehari K, Izadi Mood Z. Clinical evaluation of 625 patients with lacunar syndrome. Turkish Journal of Medical Sciences 2009; 32:1-7

Ghandehari K, Shuaib A. Evaluation of obesity and low mobility in stroke patients. Arya Atherosclerosis. 2008;4(2):23-5.

Ghandehari K, Shams M, Atalu A, Afzalnia A, Ahmadi F, Khazaei M, et al. Oral contraceptive consumption and cerebral venous thrombosis in Mashhad, Iran. Internet J Neurol. 2009;11(2).

Jauch EC, Saver JL, Adams HP, Bruno A, Demaerschalk BM, Khatri P, et al. Guidelines for the early management of patients with acute ischemic stroke a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013 ;44(3):870-947.

How to Cite
Ghandehari, K. (2016). Epidemiology of Stroke in Iran. Galen Medical Journal, 5(S1), 3-9. https://doi.org/10.31661/gmj.v5iS1.588