Epidemiologic and Clinical Aspects of Tuberculosis in Hamadan, Iran, from 2002 to 2008

Peyman Eini, Saadat Torabian, Amir Hossein Rahighi, Sepideh Mikaeilinia

Background: One-third of the world’s population is currently infected by tubercle bacillus. This study was performed to evaluate epidemiological and clinical aspects of confirmed cases of tuberculosis infections in a seven-year time period, between years of 2002 to 2008, in the city of Hamadan, west of Iran.

Materials and Methods: In this descriptive retrospective study, medical records of 375 patients from the year of 2002 to 2008 were evaluated and analyzed. Required data were obtained from medical records of all the patients and inserted into a detailed checklist. Obtained data were analyzed by using SPSS statistical software (version 11.0).                                                                                                     

Results: The mean age of the patients was 53.69±20.37. Most patients were female (58.7%). 78.1% of the cases were from urban areas. 58.7% of the patients were diagnosed by pulmonary tuberculosis. The mean age of the patients with extra-pulmonary tuberculosis was significantly younger than patients suffering from pulmonary tuberculosis. 29.1% of males and 47% of females had extra-pulmonary tuberculosis. 72.2% of the patients with pulmonary tuberculosis had a positive-sputum smear. Most patients with positive-smear for pulmonary tuberculosis were diagnosed (53%). Sputum culture was the most frequent diagnostic technique used in patients with negative-sputum smear. In patients suffering from extra-pulmonary tuberculosis, lymph node involvement was the most frequent (34.2%). 44 patients (11.7%) were expired.

Conclusion: Due to the increasing number of tuberculosis infections from 2005 to 2008, it is important for the health care providers and department of public health to monitor and pursue screening and prevention guidelines closely.
Pulmonary tuberculosis; extra-pulmonary tuberculosis; clinical manifestation; epidemiology

Raviglione MC, O’Brien RJ. Tuberculosis In: Longo, Fauci AS, Kasper DL, et al. Harrison’s principles of internal medicine.18th Edition, McGraw Hill 2011:1340-1359.

Fitzgerald DW, Sterling TR, Haas DW. Mycobacterium tuberculosis In: Mandell GL, Bennets JE, Dolin R. Principles and practice of infectious disease. 7th Edition: Philadelphia, Elsevier Churchill Livingstone. 2010: 3129-3163.

Isfahanizadeh P. Pulmonary Tuberculosis. 1th Edition: Mashahd, Ferdowsi University Press. 1987.

Tuberculosis 30 May 2005 (on line) available at: http: who in (Mediacent) fact sheets/fsl 4/ex.

Enarson DA, Murray IF. Global epidemiology of tuberculosis. In: Rom WN Gray S eds: Tuberculosis. New York: Little Brown and company 1996:67-75.

Rouillon A, Perdrizet S, Parrot R. Transmission of tubercle bacilli: The effects of chemotherapy. Tubercle. 1976; 57(4):275-99.

Iseman MD. Tuberculosis In: Goldman L, Ausiello D. Cecil medicine. 23rd Edition: Saunders 2007:1894-1902.

Ahmad Rajabi R., Abazari F. Epidemiology of tuberculosis in Bam (1995–2000). Hormozgan Medical Journal. 2002;6(3):41-46.

Ebrahimzadeh A, Sharifzadeh Gh.R, Eshaghi S. The epidemiology of Tuberculosis in Birjand (1996-2006). Journal of Birjand University of Medical Sciences. 2009;16(1):31-39

Sofian M, Zarinfar N, Mirzaee M, Moosvi nejad A. Epidemiology of tuberculosis in Arak, Iran. Koomesh Journal of Semnan University of Medical Sciences. 2009;10(4):261-266.

Khavandegaran F. Shafieyan S. Epidemiology of tuberculosis in children in Fars province. National congress of tuberculosis in Sanandaj; 2007.

Amani F, Bashiri J, Sabzevari A, Garoosi B, Nahan Moghadam N. Epidemiology of Tuberculosis in Ardabil, 2001-2005. Research & Scientific Journal of Ardabil University of Medical Sciences. 2007;7(3):236-241.

Rafie A, Mirzaaghazadeh A, Ghorbani Haghjoo A, Naghili B. Epidemiology of tuberculosis in Hashtrood – East Azarbayejan. Medical Journal of Tabriz University. 2001;35(49):39-44.

Mohamadi Azni S, Mansourian A.A, Nokandeh Z. Epidemiological study of tuberculosis in Damghan city (Iran) during 2003-2007. Koomesh Journal of Semnan University of Medical Sciences. 2008;9(4):315-319.

Moradi Gh, Eftekhar Ardebili H, Rahimi A, Esmaeilnasab N, Ghaderi A. Epidemiologic study of pulmonary tuberculosis in Kurdistan province from 2000 until 2001. Iranian Journal of Infectious Diseases and Tropical Medicine. 2006; 11(34):49-53.

Salek S, Masjedi M.R, Salek S, Emami H. Incidence Rate of Pulmonary Tuberculosis among Different Ethnicities in Golestan Province from 1999 to 2003. Iranian Journal of Epidemiology. 2008;3(3&4):15-20.

Mohammadpoor A, Fani MJ, Matlabi M, Shams H. Epidemiology of Tuberculosis in Gonabad, 1993-2001. Ofogh-e-Danesh. 2002; 8(1):45-51.

Mardani M. Extrapulmonary tuberculosis and study of 146 cases. Journal of Isfahan Medical School. 2000;18(58):55-58.

Metanat M, Salehi M, Sharifi Mood B, Jahantigh A, Rohani Z. Epidemiological study of extrapulmonary TB in Zahedan. Journal of Zahedan University of Medical Sciences. 2006;7(4):275-281.

Rokni F, Etemadi J. Epidemiological study of extrapulmonary TB in Mashhad, 1997-2001. Journal of Mashhad University of Medical Sciences. 2002;45(78):23-29.

Aminzade Z, Akhyani H. Clinical presentation of extrapulmunary tuberculosis in patients admitted in Loqmqne Hakim hospital. Tabibe sharq. 2006;7(4): 283-8.

Shafiq A, Siadati S. Pleural and extrapulmonary TB in Shahid beheshti hospital Babol in 14 years. Journal of Gorgan University of Medical Sciences. 2005;6(14):61-5.

Bonadio M, Carpi A, Gigli C, Virgone E, Carneglia L. Epidemiological and clinical features of 139 patients with tuberculosis at a teaching hospital in Italy (Pisa, 1996-2000). Biomed Pharmacother. 2005; 59(3): 127-31.

Metanat M, Sharifi-Mood B, Alavi-Naini R, Aminianfar M. The epidemiology of tuberculosis in recent years: Reviewing the status in south-eastern Iran. Zahedan J Res Med Sci (ZJRMS). 2012; 13(9): 1-7.

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